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starlaugh
08-06-2007, 10:44 AM
A team of Canadian surgeons got a shock when the patient they were operating on began shedding dark greenish-black blood, the Lancet reports.


The 42-year-old man emulated Star Trek's Mr Spock - a Vulcan who had green blood. Instead, the unusual colour of his blood was down to the migraine medication he was taking.

The man's leg surgery went ahead successfully and his blood returned to normal once he eased off the drug.

Dark green

The patient had been taking large doses of sumatriptan - 200 milligrams a day. This had caused a rare condition called sulfhaemoglobinaemia, where sulphur is incorporated into the oxygen-carrying compound haemoglobin in red blood cells.

Describing the case in The Lancet, the doctors led by Dr Alana Flexman from St Paul's Hospital in Vancouver wrote: "The patient recovered uneventfully, and stopped taking sumatriptan after discharge. "When seen five weeks after his last dose, he was found to have no sulfhaemoglobin in his blood."

The man had needed urgent surgery because he had developed a dangerous condition in his legs after falling asleep in a sitting position.
The surgeons performed urgent fasciotomies, limb-saving procedures which involve making surgical incisions to relieve pressure and swelling caused by the man's condition - compartment syndrome.

In compartment syndrome, the swelling and pressure in a restricted space limits blood flow and causes localised tissue and nerve damage. It is commonly caused by trauma, internal bleeding or a wound dressings or cast being too tight.
According to the fictional TV series Star Trek, Mr Spock of the starship Enterprise had green blood because the oxidizing agent in Vulcan blood is copper, not iron, as it is in humans.



How fucked up is that! :you_crazy I wouldn't know what to think if i had to patch someone up who is leaking dark green blood!!!!

Well i am gonna read the full report in the Lancet in a bit...

Raj
08-06-2007, 10:45 AM
Its green if you cut yourself while sports diving too :wink:

starlaugh
08-06-2007, 10:47 AM
Its green if you cut yourself while sports diving too :wink:

Really...... well i thought i had kinda got to grips with the human body and life... but now green blood?

Its all a little strange to me now :weee:

Playground Politics
08-06-2007, 01:58 PM
heres a fact(learned from Biologay) umm if ther was no oxygen in the atmosphere(aparty from dieing) our blood would br bluey purple not red, this is because as soo as we cut ourselves in the atmosphere the blood oxiginates and resumes to red, this is why are veigns are blue purple

FACT

Space Master
08-06-2007, 03:18 PM
How fucked up is that! :you_crazy I wouldn't know what to think if i had to patch someone up who is leaking dark green blood!!!!

Well i am gonna read the full report in the Lancet in a bit...

Sumatriptan is similar to LSD if i remember rightly (used for chronic migraines).

Raj
08-06-2007, 07:03 PM
Not sure you are thinking of sumitriptophan as much as ergotamine tartrate SM ;)

[ergotamine is the natural form of LSD to which I believe you are referring]

Space Master
08-06-2007, 07:09 PM
Nah, i was doing a project on hallucinogens amongst other things and i came across an article on Sumatriptan. I think it binds to serotonin sites stronger than LSD or something.

Ergotamine is more similar to LSD. There's looooads of molecules out there, even lots of different types of LSD, that's why Hoffman's LSD was called LSD-25 to show which version it was.

LSD and sumatriptan have both been compared in the treatment of headaches, i just checked on Google.

Raj
08-06-2007, 07:12 PM
I was fed sumitriptophan for migraines - wasnt much good or in any way enjoyable for me - you can take this stuff for fun?

Did you find the research were they used LSD itself as a treatment for migraines :weee: now that could be interesting....

Space Master
08-06-2007, 07:18 PM
Nah, just cos it's structurally similar doesn't mean it will get you off, there's a language these molecules talk and apparently nobody fully understands it, and that's partly why they just ban all molecules that just look like an hallucinogenic molecule.

LSD was tried on its own. As was psilocybin and Sumatriptan.

I went back to look at the articles, they are all on eJournals that you have to pay expensive subscription fees to look at, EXCEPT ....

The MAPS journal (MAP = Multidisciplinary Association for Psychedelic Studies)!!!

They are trying to get LSD back into modern lab research, as it's apparently good for cluster headaches and single headaches, and it might even be able prevent future headaches. If anyone can be asked to read it, here ya go:

www.maps.org/news-letters/v15n1/cluster.pdf

Raj
08-06-2007, 07:22 PM
I have seen LSD work for stopping a cluster mnigraine attack in its tracks when nothing else did - was pretty impressive to be fair.

Space Master
08-06-2007, 07:35 PM
Yep and ergotamine is used to ease childbirth apparently, l dunno how, i don't know if it acts as a painkiller or has some effect on increasing muscular spasms (it works on the serotonin system, serotonin = sero (= serum?) + tonin (= tension))

http://brain.oxfordjournals.org/cgi/content/full/123/1/9

Due to its remarkable uterotonic and vasoconstrictor effects, ergotamine was used to precipitate childbirth and to control post-partum haemorrhage [i.e. heavy bleeding after pregnancy]

Raj
08-06-2007, 07:40 PM
ergotamine causes strong uterine contraction and thus the effects you list above.